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Applications Key
WB = Western Blot
IP = Immunoprecipitation
IAC= Immunoaffinity Column
ChIP= Chromatin Immunoprecipitation
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Cancer Biomarkers - Cancer Antibodies arrow CA125 Monoclonal Antibody
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CA125 Monoclonal Antibody
CA125 Monoclonal Antibody
Clone: 618F Product Format: Affinity Purified
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Catalog #: N0008 - $275.00  
Size: 100 µg

Details:
Tested Applications
WB, ELISA
Target Information
CA 125 is a 250 + kDa protein
Product Format
Affinity Purified
Alternate Names
Mucin-16, MUC-16, MUC16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125, CA125
Clone
618F
Host
Mouse
Isotype
IgG1
Immunogen
Endogenous Protein
Epitope
Unknown
Relevance
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. CA125 binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.
Specificity
Human
Reported Reactivity
Mouse
Reported Applications
Flow Cytometry

Technical Data Sheet Technical Data Sheet

 

Relevant Links:

NCBI NP 418415

Swiss Prot P0A8T7

Literature Search pubmed logo

 

References:

1. Goodell CA, Belisle JA, Gubbels JA, Migneault M, Rancourt C, Connor J, Kunnimalaiyaan M, Kravitz R, Tucker W, Zwick M, Patankar MS. (2009). Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies. J. Ovarian Research, 2:8 pubmed logo

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