ANTIBODY PRODUCTS
Applications Key
WB = Western Blot
IP = Immunoprecipitation
IAC= Immunoaffinity Column
ChIP= Chromatin Immunoprecipitation
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Shiga toxin Stx2A Monoclonal Antibody |
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Clone: 4A11G10H8 Product Format: Affinity Purified
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Catalog #: SC002 -
$275.00
Size:
100 µg
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| Details: |
| Tested Applications |
WB, ELISA |
| Target Information |
A is a 35 kDa subunit of Shiga Toxin |
| Product Format |
Affinity Purified |
| Alternate Names |
SLT-2 A subunit, SLT-2a, SLT-IIa, Verocytotoxin 2 subunit A, Verotoxin 2 subunit A, rRNA N-glycosidase 2, stxA2, stx2A |
| Clone |
4A11G10H8 |
| Host |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Peptide |
| Epitope |
a.a. 61 - 75 |
| Relevance |
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subnit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits. |
| Specificity |
stxA2 |
| Reported Reactivity |
Unknown |
| Reported Applications |
Unknown |
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Technical Data Sheet 
Relevant Links:
NCBI NP 286976
Swiss Prot P09385
Literature Search  |
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Shiga toxin Stx2A Monoclonal Antibody
