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What is ascites?
What is affinity purified?

Applications Key
WB = Western Blot
IP = Immunoprecipitation
IAC= Immunoaffinity Column
ChIP= Chromatin Immunoprecipitation

NeoAbs perform to strict quality control standards. For more information about antibody performance, please see the product technical data sheet or our FAQ for applications, quality control, and reactivity.

RNA Pol II Antibodies

RNA Pol II RPB3 Monoclonal Antibody- Ascites

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RNA Pol II RPB3 Monoclonal Antibody- Ascites

Clone: 1Y26 Product Format: Ascites

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Catalog #: W0012 - $275.00

Size: 100 µl

Details:
Tested Applications	WB, ELISA
Target Information	RPB3 is a 45kDa subunit of RNA Polymerase II
Product Format	Ascites
Alternate Names	RNA polymerase II sub-unit 3, RPB3, POLR2C
Clone	1Y26
Host	Mouse
Isotype	IgG1
Immunogen	Recombinant Protein
Epitope	Unknown
Relevance	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft and seems to be involved in transcription termination.
Specificity	Yeast (Saccharomyces cerevisiae) RNA Pol II
Reported Reactivity	None
Reported Applications	ChIP

Technical Data Sheet

Relevant Links:

NCBI NP 012243

Swiss Prot P16370

Literature Search

References:

1. Svetlov,V., Nolan, K., and Burgess, R.R. (1998). Rpb3, stoichiometry and sequence determinants of the assembly into yeast RNA polymerase II in vivo. J Biol Chem 273, 10827-30.

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RNA Pol II RPB3 Monoclonal Antibody

Sample Pack: RNA polymerase II subunits