ANTIBODY PRODUCTS
Applications Key
WB = Western Blot
IP = Immunoprecipitation
IAC= Immunoaffinity Column
ChIP= Chromatin Immunoprecipitation
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RNA Pol II RPB5 Monoclonal Antibody |
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Clone: 3Y11 Product Format: Ascites
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Catalog #: W0014 -
$275.00
Size:
100 µl
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| Details: |
| Tested Applications |
WB |
| Target Information |
RPB5 is a 27kDa subunit of yeast RNA polymerase II. |
| Product Format |
Ascites |
| Alternate Names |
DNA-directed RNA polymerases I, II, and III subunit RPABC1, PolR2E, RNA polymerases I, II, and III subunit ABC1, RPA7, RPC9 |
| Clone |
3Y11 |
| Host |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Recombinant Protein |
| Epitope |
Unknown |
| Relevance |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process |
| Specificity |
Yeast (Saccharomyces cerevisiae) RNA Pol II |
| Reported Reactivity |
None |
| Reported Applications |
Unknown |
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Technical Data Sheet 
Relevant Links:
NCBI NP 009712
Swiss Prot P20434
Literature Search  |
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RNA Pol II RPB5 Monoclonal Antibody
